医学部坐倚珞珈山,环绕东湖水,绿树成荫,花香流溢。学部源于1943年成立的湖北省省立医学院,现在是武汉大学六大学部之一。 学部含基础医学院、第一临床学院、第二临床学院、口腔医学院、药学院、健康学院、职业技术学院...

地址: 湖北省武汉市武昌区东湖路115号
电话:027-68759376
中国科学院院士: 邓子新舒红兵
国家级教学名师: 樊明文边专
国家杰出青年基金获得者: 邓子新舒红兵郭德银章晓联万芪李红良
千人计划入选: 霍文哲张发明、于学杰
青年千人计划入选: 陈实蒋卫钟波张好建、陈强、罗孟成、邓迎峰
百千万人才工程选者: 舒红兵、黄从新章晓联 
长江学者: 董晨舒红兵李红良
万人计划: 领军人才:舒红兵唐其柱李红良   青年拔尖人才: 刘天罡 、王连荣王培刚                
教育部新世纪优秀人才: 何小华 于红刚 李雁郑芳、胡锦跃、黄鹤
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姓名:吴莹

单位:武汉大学医学部基础医学院医学病毒学研究所

职称:研究员、副教授

邮箱:yingwu@whu.edu.cn

联系电话:(暂无)

研究方向:

1.病毒与宿主互作的分子机制:解析病毒蛋白与宿主因子相互作用的结构基础,阐明相互作用的分子机制

2.病毒治疗性抗体:筛选传染性病毒治疗性抗体并解析其作用机制


 









代表性论著:

通讯作者和共同通讯作者(*)

1.Ying Wu*, Yan Wu, Boris Tefsen, Yi Shi, George F. Gao*. Bat-derived influenza-like viruses H17N10 and H18N11. Trends in Microbiology, 22(4): 183-91, 2014.

2.Ying Wu*, George F. Gao*. Lessons learnt from the human infections of avian-origin influenza A H7N9 virus: Live free markets and human health. Science China. Life sciences, 56: 6: 493-4, 2013.

3.Ying Wu*, George F. Gao*. Severe fever with thrombocytopenia syndrome virus expands its borders. Emerging Microbes and Infections, 2 e36, 2013.

4.Ying Wu*, George F. Gao*. Compiling of comprehensive data of human infections with novel influenza A (H7N9) virus. Frontier of Medicine, 7(3):  275-276, 2013.

5.George F. Gao*, Ying Wu*. Haunted with and hunting for viruses. Science China. Life sciences, 56:8:675-677, 2013.

第一作者和并列第一作者(#)

6.Ying Wu#, MyungSam Cho#, David Shore#, Manki Song, JungAh Choi, Tao Jiang, Yong-Qiang Deng,Melissa Bourgeois,et al. A potent broad-spectrum protective humanmonoclonal antibody crosslinking twohaemagglutinin monomers of influenza A virus. Nature Communications, 6:7708, 2015. 

7.Yi Shi#, Wei Zhang#, Fei Wang#, Jianxun Qi# , Ying Wu#, Hao Song, Feng Gao, Yuhai Bi, et al. Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses. Science, 342:243-247, 2013.

8.Ying Wu, Christopher J Vavricka, Yan Wu, Qing Li, Santosh Rudrawar, Robin J. Thomson, Mark von Itzstein, George F. Gao,et al.Atypical group1 neuraminidase pH1N1-N1 bound to a group1 inhibitor. Protein & Cell, 6(10):771-773, 2015.

9.Ying Wu, Changzhen Liu, Meiyi Sun, Hexiao Shen, Deyin Guo, Bin Gao.A specific cytotoxic T-lymphocyte epitope presentation system for antitumor immunity. International Journal of Cancer , 126(10):2373-86, 2009.

其他部分合作文章:

10.Di Liu, Weifeng Shi, Yi Shi, Dayan Wang, Haixia Xiao, Wei Li, Yuhai Bi, Ying Wu, XianbinLi, Jinghua Yan, Wenjun Liu, Guoping Zhao, Weizhong Yang, Yu Wang, Juncai Ma, Yuelong Shu, Fumin Lei, George F. Gao, Origin and diversity of novel avian influenza A H7N9 viruses causing human infection: phylogenetic, structural, and coalescent analyses. Lancet, 381:1926-32, 2013.

11.Yi Shi, Ying Wu, Wei Zhang, JianXun Qi, George F. Gao, Enabling the 'host jump': structural determinants of receptor-binding specificity in influenza A viruses. Nature Reviews Microbiology, 12: 822-31, 2014.

12.Lunbiao Cui, Di Liu, Weifeng Shi, Jingcao Pan, Xian Qi, Xianbin Li, XilingGuo, Minghao Zhou, Wei Li, Jun Li, Joel Haywood, Haixia Xiao, Xinfen Yu, Xiaoying Pu, Ying Wu, Huiyan Yu, Kangchen Zhao, Yefei Zhu, Bin Wu, Tao Jin, Zhiyang Shi, Fenyang Tang, FengcaiZhu,Qinglan Sun,Linhuan Wu, Ruifu Yang, Jinghua Yan, Fumin Lei, Baoli Zhu, Wenjun Liu, Juncai Ma, Hua Wang, George F. Gao, Dynamic reassortments and genetic heterogeneity of the human-infecting influenza A (H7N9) virus. Nature Communications, 5: 3142, 2013.

13.Fengming Huang, Jing Guo, Zhen Zou, Jun Liu, Bin Cao, Shuyang Zhang, Hui Li, Wei Wang, Miaomiao Sheng, Song Liu,Jingcao Pan, ChangjunBao, Mei Zeng, Haixia Xiao, GuirongQian, XinjunHu,Yuanting Chen, Yu Chen, Yan Zhao, Qiang Liu, Huandi Zhou, JingdongZhu,Hainv Gao, Shigui Yang, Xiaoli Liu, Shufa Zheng, Jiezuan Yang, HongyanDiao, Hongcui Cao, Ying Wu, Min Zhao, Shuguang Tan, Dan Guo, Xiliang Zhao, Yicong Ye, Wei Wu, Yingchun Xu, Josef Penninger,Dangsheng Li, George F Gao, Chengyu Jiang, Lanjuan Li, Angiotensin II plasma levels are linked to disease severity and predict fatal outcomes in H7N9-infected patients. Nature Communications, 6: 5: 3595, 2014.

14.  Yan Li, Yuhua Wan, Peipei Liu, Jincun Zhao, Guangwen Lu, Jianxun Qi, Qihui Wang, Xuancheng Lu, Ying Wu, Wenjun Liu, Buchang Zhang, Kwok-Yung Yuen, Stanley Perlman, George F Gao, Jinghua Yan. A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein. Cell Research, 25(11):1237-49, 2015.

15.  Min Wang, Wei Zhang, Jianxun Qi, Fei Wang, Jianfang Zhou, Yuhai Bi, Ying Wu, Honglei Sun, Jinhua Liu, Chaobin Huang, Xiangdong Li, Jinghua Yan, Yuelong Shu, Yi Shi, George F Gao. Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus. Nature Communications, 6:5600, 2015.