医学部坐倚珞珈山,环绕东湖水,绿树成荫,花香流溢。学部源于1943年成立的湖北省省立医学院,现在是武汉大学六大学部之一。 学部含基础医学院、第一临床学院、第二临床学院、口腔医学院、药学院、健康学院、职业技术学院...

地址: 湖北省武汉市武昌区东湖路115号
电话:027-68759376
中国科学院院士: 邓子新舒红兵
国家级教学名师: 樊明文边专
国家杰出青年基金获得者: 邓子新舒红兵郭德银章晓联万芪李红良
千人计划入选: 霍文哲张发明、于学杰
青年千人计划入选: 陈实蒋卫钟波张好建、陈强、罗孟成、邓迎峰
百千万人才工程选者: 舒红兵、黄从新章晓联 
长江学者: 董晨舒红兵李红良
万人计划: 领军人才:舒红兵唐其柱李红良   青年拔尖人才: 刘天罡 、王连荣王培刚                
教育部新世纪优秀人才: 何小华 于红刚 李雁郑芳、胡锦跃、黄鹤
图片1.png

姓名:陈璞

单位:武汉大学 基础医学院 生物医学工程系

职称:教授、博导

邮箱:puchen@whu.edu.cn

联系电话:138-7156-7947

研究方向:

1.组织工程与再生医学:以微尺度组织工程和微流控芯片技术为依托,构建微组织、类器官、组织器官芯片、人体芯片等人体微生理和病理体外模型,服务于人体生理、病理等基础医学研究,尤其是代谢相关性疾病研究,以及药物筛选、个性化医疗等转化医学研究。

2.体外诊断颠覆性技术开发:以微流控芯片和微声光机电系统为依托,开发针对心血管、肝脏、代谢相关性疾病的体外、早期、快速、诊断技术。


 











代表性论著:

1.Pu Chen, Sinan Güven, Osman Berk USTA, Martin L. Yarmush and Utkan Demirci. Scaffold-free spheroid assembly to generate organoids, Tissue Engineering Part A, 2015, 21: S27-S27. (IF: 4.448) 

2.Pu Chen, Zhengyuan Luo, Sinan Güven, Savas Tasoglu, Adarsh V Ganesan, Andrew Weng and Utkan Demirci*. Microscale assembly directed by liquid-based template. Advanced Materials, 2014, 26(34), 5936-41. (IF: 17.49) (Featured on the cover of the journal, Reported by Materials View, NewScientist)

3.Pu Chen, Sinan Guven and Utkan Demirci. Scaffold-free cell assembly for tissue engineering. Journal of Tissue Engineering and Regenerative Medicine, 2014, 8:59. (IF: 5.199)

4.Pu Chen, Xiaojun Feng, Rui Hu, Jian Sun, Wei Du and Bi-Feng Liu*. Hydrodynamic gating valve for microfluidic fluorescence-activated cell sorting. Analytica Chimica Acta, 2010, 663: 1-6. (IF: 4.31) (Featured article of the issue)

5.Pu Chen, Xiaojun Feng, Wei Du, Bi-Feng Liu*. Microfluidic chips for cell sorting. Frontier in Bioscience, 2008, 13: 2464-2483. (IF: 3.5)

6.Pu Chen#, Shuqi Wang#, Fatih Inci, Sinan Güven, Savas Tasoglu and Utkan Demirci. Cell-encapsulating Hydrogels for Biosensing. Gels Handbook: Fundamentals, Properties and Applications, eds Sheereen Majd and Lifeng Kang (World Scientific Publishing Co., Singapore) 2016.

7.Pu Chen#, Sinan Guven#, Berk Usta, Martin Yarmush and Utkan Demirci*. Bio-tunable acoustic node assembly of organoids, Advanced Healthcare Materials, 2015, 4(13), 1937–1943. (Co-first author, IF: 5.76)

8.Pu Chen#, Xiaojun Feng#, Jian Sun, Ying Wang, Wei Du and Bi-Feng Liu*. Hydrodynamic gating for sample introduction on a microfluidic chip. Lab on a Chip, 2010, 10: 1472-1475. (Co-first author, IF: 6.26)

9.Vahid Serpooshan#, Pu Chen#, Haodi Wu, Soah Lee, Arun Sharma, Daniel A Hu, Sneha Venkatraman, Adarsh Ganesan, Berk Usta, Martin Yarmush, Fan Yang, Joseph C Wu, Utkan Demirci,  Sean M Wu, Bioacoustic-enabled patterning of human iPSC-derived cardiomyocytes into 3D cardiac tissue. Biomaterials, 2017, 131,47. (IF: 8.978)

10.Yiwei Li#, Pu Chen#, Yachao Wang, Shuangqian Yan, Xiaojun Feng, Wei Du, Stephan A. Koehler, Utkan Demirci and Bi-Feng Liu*. Rapid assembly of heterogeneous three-dimensional cell microenvironments in microgel array, Advanced Materials, 2016, 28(18), 3543–3548 (Co-first author, IF: 18.9)  

11.Charlène bouyer#, Pu Chen#, Sinan Guven#, Tugrul Tolga Demirtas, Thomas J.F Nieland, Frédéric Padilla and Utkan Demirci*. A bio-acoustic levitational (BAL) assembly method for engineering of multilayered, three-dimensional brain-like constructs, using human embryonic stem cells derived neuro-progenitors, Advanced Materials, 2015, 28(1), 161–167. (Co-first author, IF: 18.9)  

12.Sinan Guven#, Pu Chen#, Fatih Inci, Savas Tasoglu, Burcu Erkmen and Utkan Demirci*. Multiscale Assembly for Tissue Engineering and Regenerative Medicine. Trends in Biotechnology, 2015, 133(5), 269-279. (Co-first author, IF: 11.9) 

13.Rami El Assal#, Pu Chen# and Utkan Demirci*. Highlights from the latest articles in advanced biomanufacturing at micro- and nano-scale, Nanomedicine, 2015, 10, 347-350 (Co-first author, IF: 5.4) 

14.Liang Wu#, Pu Chen#, Yingsong Dong, Xiaojun Feng and Bi-Feng Liu* (2013) Encapsulation of single cells on a microfluidic device integrating droplet generation with fluorescence-activated droplet sorting. Biomedical Microdevices, 2013, 15(3):553-60. (Co-first author, IF: 2.9) 

15.Jian Sun#, Pu Chen#, Xiaojun Feng, Wei Du and Bi-Feng Liu*. Development of a microfluidic cell-based biosensor integrating a millisecond chemical pulse generator. Biosensors and Bioelectronics, 2011, 26(8): 3413-3419. (Co-first author, IF: 6.4) 

16.Charlène Bouyer, Pu Chen, Sinan Güven, Tugrul Tolga Demirtas, Frederic Padilla and Utkan Demirci, Acoustic printing of multilayer neuronal networks, Tissue Engineering Part A, 2015, 21: S27-S28. (IF: 4.448)

17.Charlène bouyer, Pu Chen, Thomas J.F Nieland, Utkan Demirci, and Frederic Padilla, Bio-acoustic levitational assembly of heterocellular 3D constructs: 3D model establishment for cells radiation effect studies in 3D microenvironment. Physica Medica, 2016. 32: 214.

18.Charlene. Bouyer, Pu Chen, Utkan Demirci, Fred Padilla. Bio-acoustic levitational assembly of heterocellular multilayer constructs for tissue engineering, The Journal of the Acoustical Society of America 2016, 140, 3370.

19.Peng Chen, Pu Chen, Xiaojun Feng, Wei Du and Bi-Feng Liu*. Analysis of intercellular communication by flexible hydrodynamic gating on a microfluidic chip. Analytical and Bioanalytical Chemistry, 2013, 405(1):307-314. (IF:: 3.4) 

20.Savas Tasoglu, Doga Kavaz, Umut A Gurkan, Sinan Guven, Pu Chen, Rela Zheng and Utkan Demirci*. Paramagnetic Levitational Assembly of Hydrogels. Advanced Materials, 2013, 25(8):1137-1143. (IF:17.5) (Featured on the cover of the journal)